After 8 years of having zero mobility because of hyper-extended knee joints and a failed knee replacement, followed by a multitude of linked issues such as rotator cuff shoulders (extremely painful) and suspected polyps (I am still waiting for a hospital report, three weeks after a CT scan) - I now have puffed up ankles, lower calves - possibly the result of too high dose of amlodipine - which I am taking for high blood pressure (and successfully lowered it)…